Diagnostic confirmation of freedom from the pathogen is a key component of the eradication program, and allows for better-informed decisions when measuring success. Moreover, diagnostic confirmation provides the opportunity to prevent failure following the significant investment by implementing a contingency plan; for example, extending the herd closure, delaying entry of naïve replacement gilts, etc.

The diagnostic approach for confirmation of eradication program completion needs to be science-based, utilizing epidemiological principles that are specific for M. hyopneumoniae.

The sole completion of a timeline or the application of a program, without diagnostic confirmation, may not imply eradication success.