Although limited information is available on survivability of M. hyopneumoniae in the environment, dust has been implicated as a reservoir, necessitating cleaning and disinfection of gestation barns, farrowing rooms and GDUs as a component of the herd closure program. Viability of M. hyopneumoniae may be longer than expected on different surfaces and future work should be directed to this area. Culture of M. hyopneumoniae is challenging, and sample cross-contamination with environmental residual genetic material can occur and be detected via PCR, even though it may not be viable. New tools like the viability PCR offer methods to better explore M. hyopneumoniae environmental stability.