Once the eradication program has been completed and successful elimination has been confirmed, negative gilts may be introduced into the sow herd.

If replacement gilts are purchased from a multiplier, it is critical that the producer and consulting veterinarian have worked with the genetic supplier and production company to confirm M. hyopneumoniae negative status, as well as agree to a surveillance protocol, both at the supplier sow farm and gilt grow-out sites.

Prior to the entry of M. hyopneumoniae–naïve replacement gilts, the producer and veterinarian should have established the biosecurity plan, including the final cleaning and disinfection of the facilities and trailers, the plan for the isolation/quarantine of incoming gilts, and have communicated with the breeding stock supplier the number of gilts and frequency of delivery required upon resumption of gilt entry.

The use of interventions at each phase of production and adjustments to protocol should be discussed and redefined in preparation for final confirmation of M. hyopneumoniae negative status.